Involvement of N - Acetylcysteine - sensitive in Ricin - induced Apoptotic Cell Death inPathwaysU 937 Cells
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چکیده
We have foulld that the antioxidant Nacetylcysteine (NAC) strongly inhibited ricin-induced apoptotic cell death in U937 cells (human myeloid leukemia), as judged by cytotoxicity, nuclear morphological change, and DNA fragmentation. Consistent with these observations, a significant depletion of cel}ular glutathiene was observed i" ricin-treated cells, and NAC prevented the decrease in cellular
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تاریخ انتشار 2018